microelectrode recording
Also written as: MER — microelectrode recording
Technique using extremely fine electrodes to record electrical activity from individual neurons or small groups of cells.
Full Definition
Microelectrode recording is an electrophysiological technique that uses electrodes with tip diameters of 1-10 micrometers to record electrical activity from single neurons or small clusters of brain cells. This method provides extremely high spatial resolution, allowing researchers and clinicians to study individual cell firing patterns, local field potentials, and neuronal responses to stimuli. In clinical settings, microelectrode recording is commonly used during deep brain stimulation (DBS) surgery to precisely locate target structures and confirm optimal electrode placement. The technique requires specialized amplification equipment due to the small signal amplitudes recorded.
Usage
Usage note: Hyphenate when used as adjective modifier; MER acceptable as abbreviation in technical contexts.
In Context
- "Microelectrode recording confirmed the characteristic firing patterns of subthalamic nucleus neurons." — DBS surgery report
- "Single-unit activity was monitored using microelectrode recording techniques." — Neurophysiology research