connectome
Pronunciation: con-nect-ohm
Comprehensive map of neural connections within the brain, derived from neuroimaging data.
Full Definition
The connectome refers to a comprehensive map of neural connections within an organism's nervous system, typically derived from diffusion MRI tractography or functional connectivity analysis. Human connectome mapping involves identifying and quantifying both structural pathways (white matter tracts) and functional connections (correlated activity patterns) between brain regions. Connectomic analysis has revealed fundamental principles of brain organization including small-world topology, rich-club architecture, and modular community structure that are altered in various neurological and psychiatric conditions.
Usage
Usage note: Capitalize 'Human Connectome Project' as proper noun; lowercase 'connectome' as general term.
In Context
- "The Human Connectome Project has mapped structural and functional connectivity in 1,200 healthy adults." — Research consortium description
- "Connectome analysis revealed disrupted rich-club organization in patients with schizophrenia." — Clinical neuroscience study