CSF cytology
Microscopic examination of cerebrospinal fluid cells to detect abnormal or malignant cells.
Full Definition
CSF cytology involves the microscopic examination of cells present in cerebrospinal fluid to identify abnormal cellular populations, including malignant cells, inflammatory cells, or infectious organisms. This diagnostic technique is particularly valuable in suspected CNS malignancies, chronic meningitis, and certain autoimmune conditions. The procedure requires careful collection and rapid processing of CSF samples, as cellular morphology can deteriorate quickly. Cytological findings must be interpreted in conjunction with clinical presentation and other laboratory parameters.
Usage
Usage note: Distinguish from simple cell counts by emphasizing morphological assessment.
In Context
- "CSF cytology revealed atypical lymphoid cells consistent with CNS lymphoma." — Pathology report
- "The lumbar puncture sample was sent for routine analysis and CSF cytology." — Laboratory orders