surface-based morphometry
Analytical approach that measures cortical properties like thickness, area, and curvature on reconstructed brain surfaces rather than in volumetric space.
Full Definition
Surface-based morphometry is a neuroimaging analysis technique that quantifies cortical anatomy by measuring properties such as thickness, surface area, volume, and curvature on reconstructed three-dimensional brain surfaces. This approach offers advantages over volume-based methods by respecting the intrinsic topology of the cortex, enabling more precise inter-subject comparisons, and providing better localization of cortical changes. Surface-based morphometry is widely used in developmental studies, aging research, and investigations of neurological and psychiatric disorders.
Usage
Usage note: Hyphenate consistently; distinguish clearly from volume-based approaches in comparative contexts.
In Context
- "Surface-based morphometry revealed localized cortical thinning in the patient group." — Neurological research paper
- "The study employed surface-based morphometry to achieve optimal inter-subject cortical alignment." — Methodology section