voxel
Pronunciation: VOX-el
A three-dimensional unit of measurement in brain imaging, representing volume pixels.
Full Definition
A voxel (volumetric pixel) is the basic unit of measurement in three-dimensional brain imaging data, representing a cubic volume element within the brain. Each voxel contains a single intensity value that represents the measured signal (such as BOLD response in fMRI) at that spatial location. Voxel size determines the spatial resolution of neuroimaging data and affects statistical power in neuroinformatics analyses. Typical voxel sizes in fMRI range from 2-4 millimeters on each side, balancing spatial resolution with signal-to-noise ratio.
Usage
Usage note: Singular 'voxel', plural 'voxels'; not 'voxles' or 'voxals'.
In Context
- "The analysis was performed at the voxel level with a significance threshold of p < 0.001." — Methods section
- "Voxel-wise statistical maps were generated using general linear modeling." — Technical report