CIDP
Also written as: CIDP — Chronic Inflammatory Demyelinating Polyneuropathy
Chronic Inflammatory Demyelinating Polyneuropathy. An acquired autoimmune peripheral nerve disorder requiring specific diagnostic criteria and treatment protocols.
Full Definition
Chronic Inflammatory Demyelinating Polyneuropathy (CIDP) is an acquired autoimmune disorder affecting peripheral nerves, characterized by progressive weakness and sensory loss over at least 8 weeks. Unlike acute inflammatory demyelinating polyneuropathy (Guillain-Barré syndrome), CIDP follows a chronic course with either progressive or relapsing-remitting patterns. Diagnosis requires specific electrodiagnostic criteria including prolonged distal latencies, conduction velocities <70% of normal, and evidence of demyelination. Treatment typically involves immunomodulatory therapy such as corticosteroids, IVIG, or plasma exchange.
Usage
Usage note: Always spell out on first use in patient documents. Distinguish from acute forms (GBS/AIDP).
In Context
- "The patient met electrodiagnostic criteria for definite CIDP with conduction velocities reduced to 35 m/s in median nerves bilaterally." — Electrodiagnostic report
- "CIDP was suspected given the 6-month history of progressive weakness and absent reflexes, prompting nerve conduction studies." — Clinical assessment