Myositis ossificans
Pronunciation: my-oh-SY-tis ah-SIF-ih-kanz
Heterotopic bone formation within muscle tissue, typically following trauma or in genetic conditions. Creates characteristic calcification patterns on imaging.
Full Definition
Myositis ossificans is the formation of bone and cartilage within muscle tissue, occurring either as a localized response to trauma (myositis ossificans traumatica) or as part of a systemic genetic disorder (myositis ossificans progressiva, now called fibrodysplasia ossificans progressiva). The traumatic form typically develops 2-4 weeks after muscle injury, while the hereditary form follows a predictable anatomical progression. Diagnosis is confirmed by characteristic imaging findings showing peripheral calcification with a lucent center ('eggshell' pattern). Differentiation from malignant soft tissue tumors is crucial, as biopsy of suspected myositis ossificans can trigger further ossification.
Usage
Usage note: Distinguish between traumatic and hereditary forms. Avoid biopsy if possible to prevent exacerbation.
In Context
- "CT imaging revealed myositis ossificans in the quadriceps with characteristic peripheral calcification and central lucency." — Radiology report
- "The patient developed myositis ossificans six weeks following blunt trauma to the anterior thigh." — Sports medicine consultation