ocular myasthenia gravis
Also written as: OMG — ocular myasthenia gravis
A localized form of myasthenia gravis affecting only the extraocular muscles and eyelids.
Full Definition
Ocular myasthenia gravis is a subtype of myasthenia gravis characterized by weakness limited to the extraocular muscles and levator palpebrae, resulting in ptosis, diplopia, and ocular motility dysfunction without generalized muscle involvement. Approximately 10-15% of myasthenia gravis cases remain purely ocular throughout the disease course, while others may progress to generalized myasthenia within two years. Patients typically present with fluctuating ptosis that worsens with sustained upward gaze and variable diplopia. Diagnosis relies on clinical presentation, positive anticholinesterase testing, and sometimes specialized antibody testing. Treatment includes cholinesterase inhibitors and may require immunosuppressive therapy for refractory cases.
Usage
Usage note: Specify 'ocular' to distinguish from generalized myasthenia gravis.
In Context
- "The patient's isolated ptosis and diplopia suggested ocular myasthenia gravis." — Ophthalmology consultation
- "Ocular myasthenia gravis responded well to pyridostigmine therapy." — Follow-up visit note