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medulloepithelioma
Pronunciation: meh-dul-oh-ep-ih-thee-lee-OH-mah
A rare primitive neuroectodermal tumor that recapitulates the embryonic neural tube.
Full Definition
Medulloepithelioma is a rare WHO grade IV primitive neuroectodermal tumor that histologically mimics the embryonic neural tube or medullary epithelium. These tumors typically arise in young children and demonstrate characteristic flexner-wintersteiner-like rosettes and true rosettes. The tumor cells are arranged in tubular or rosette-like structures reminiscent of the primitive neural tube. Prognosis is generally poor due to the aggressive nature and tendency for CSF dissemination.
Usage
Usage note: Distinguish from ependymoma by embryonic neural tube morphology.
In Context
- "The pediatric case showed classic medulloepithelioma features with prominent rosette formation." — Neuropathology report
- "Medulloepithelioma was confirmed by the presence of true rosettes and primitive neuroectodermal morphology." — Diagnostic consultation
Also known as
primitive medulloepithelioma
Don't confuse with
ependymoma
primitive neuroectodermal tumor