medication-induced parkinsonism
Pronunciation: PAR-kin-son-izm
Reversible movement disorder caused by medications that block dopamine receptors, mimicking the symptoms of Parkinson's disease.
Full Definition
Medication-induced parkinsonism is an iatrogenic movement disorder that develops as a side effect of medications that block or deplete dopamine, particularly antipsychotic medications and certain antiemetics. The condition presents with classic parkinsonian symptoms including bradykinesia, rigidity, tremor, and postural instability that are clinically indistinguishable from idiopathic Parkinson's disease. Unlike Parkinson's disease, medication-induced parkinsonism is potentially reversible upon discontinuation or reduction of the offending medication, though recovery may take weeks to months. Risk factors include advanced age, female gender, and higher medication doses.
Usage
Usage note: Potentially reversible unlike idiopathic Parkinson's. Most commonly caused by antipsychotics. Recovery may take months.
In Context
- "The patient's medication-induced parkinsonism improved significantly after switching from haloperidol to quetiapine." — Medication management note
- "DaTscan imaging was ordered to differentiate between medication-induced parkinsonism and early Parkinson's disease." — Movement disorder consultation