ependymoma
Pronunciation: eh-PEN-dih-moh-mah
A type of brain or spinal cord tumor arising from ependymal cells that line the ventricular system.
Full Definition
Ependymomas are primary central nervous system tumors that develop from ependymal cells, which line the ventricles of the brain and the central canal of the spinal cord. These tumors can occur anywhere along the ventricular system but are most commonly found in the posterior fossa in children and the spinal cord in adults. Ependymomas are classified into three grades (Grade I, II, and III) based on their histological features and aggressiveness. Grade I lesions (myxopapillary ependymoma and subependymoma) are typically benign, while Grade III (anaplastic ependymoma) represents the most aggressive form. Treatment usually involves surgical resection followed by radiation therapy, with the extent of surgical removal being the most important prognostic factor.
Usage
Usage note: Specify grade and location when documenting for treatment planning.
In Context
- "MRI revealed a Grade II ependymoma in the fourth ventricle causing obstructive hydrocephalus." — Radiology report
- "The spinal ependymoma was successfully resected with preservation of neurological function." — Surgical summary