cerebrospinal fluid
Clear fluid that circulates within the brain ventricles and subarachnoid space, providing cushioning and metabolic support to neural tissue.
Full Definition
Cerebrospinal fluid (CSF) is a clear, colorless liquid that circulates through the ventricular system and subarachnoid space surrounding the brain and spinal cord. CSF is produced primarily by the choroid plexus and serves multiple functions including mechanical protection, metabolic support, and waste removal. In neurosurgical oncology, CSF analysis helps diagnose leptomeningeal disease, monitor for tumor cells, and assess treatment response. CSF circulation can be disrupted by tumors causing hydrocephalus, requiring surgical intervention such as shunt placement or endoscopic third ventriculostomy.
Usage
Usage note: Abbreviate as CSF after first use; hyphenate when used as compound modifier.
In Context
- "Cerebrospinal fluid analysis revealed malignant cells consistent with leptomeningeal metastases." — lumbar puncture report
- "The tumor obstructed cerebrospinal fluid flow, resulting in communicating hydrocephalus." — neurosurgical consultation