FLAIR sequence
Pronunciation: flair
Also written as: FLAIR — Fluid Attenuated Inversion Recovery
MRI imaging sequence that suppresses cerebrospinal fluid signal to enhance visualization of brain pathology adjacent to fluid spaces.
Full Definition
FLAIR (Fluid Attenuated Inversion Recovery) sequence is a specialized MRI technique that suppresses the signal from cerebrospinal fluid while maintaining contrast between gray and white matter. In neurosurgical oncology, FLAIR imaging is particularly valuable for detecting periventricular tumors, brain edema, and subtle lesions that might be masked by bright CSF signal on conventional T2-weighted images. The sequence enhances visualization of pathology near the ventricles, subarachnoid space, and cortical surface. FLAIR images often reveal tumor extent more clearly than other sequences and can demonstrate peritumoral changes, making them essential for surgical planning and monitoring treatment response. The technique is especially useful for identifying infiltrative tumor margins and associated edema.
Usage
Usage note: Always written in capital letters when abbreviated; full form should be capitalized.
In Context
- "FLAIR sequence demonstrated extensive peritumoral hyperintensity suggesting edema or infiltration." — MRI report
- "The tumor margins were best delineated on FLAIR images compared to conventional sequences." — preoperative imaging review