laser interstitial thermal therapy
Pronunciation: in-ter-STISH-al THER-mal
Minimally invasive procedure using laser energy to heat and destroy tumor tissue under MRI guidance.
Full Definition
Laser interstitial thermal therapy (LITT) is a minimally invasive neurosurgical technique that uses laser energy to create controlled thermal damage to tumor tissue. The procedure involves placing a laser fiber through a small cranial opening into the tumor under stereotactic guidance, with real-time MRI thermometry monitoring to ensure precise treatment delivery. LITT is particularly useful for deep-seated tumors, recurrent tumors in previously irradiated areas, or patients who are poor surgical candidates. The technique can achieve cytoreductive effects similar to surgical resection while minimizing trauma to surrounding normal brain tissue. Editorial staff should understand this represents an emerging treatment modality bridging surgical and radiation therapy approaches.
Usage
Usage note: Can be abbreviated as LITT after first use. Emphasize the real-time MRI guidance aspect.
In Context
- "Laser interstitial thermal therapy was selected for the deep thalamic recurrence due to surgical inaccessibility." — Treatment selection rationale
- "Real-time MRI thermometry during laser interstitial thermal therapy showed adequate treatment coverage." — Procedural report