perilesional zone
The brain tissue immediately surrounding a tumor that may contain infiltrating cancer cells or be affected by tumor-related changes.
Full Definition
The area of brain tissue directly adjacent to a tumor mass that represents a critical zone in neurosurgical oncology. This region may harbor microscopic tumor infiltration, vasogenic edema, or reactive gliosis. The perilesional zone is of particular importance in surgical planning as it represents the potential margin for tumor extension and influences decisions regarding extent of resection. Advanced imaging modalities and intraoperative techniques are employed to characterize this region and optimize surgical outcomes while preserving neurological function.
Usage
Usage note: Distinct from 'peritumoral edema' which refers specifically to fluid accumulation rather than the anatomical zone itself.
In Context
- "Histopathological analysis of the perilesional zone revealed scattered malignant cells beyond the visible tumor boundary." — Pathology report
- "The perilesional zone showed increased signal intensity on FLAIR imaging." — MRI interpretation