Intermediate
Technical
IVT
BIOT
Pronunciation: BY-aht
Also written as: BIOT — biotinidase
Abbreviation for biotinidase, an enzyme measured in newborn screening to detect biotinidase deficiency.
Full Definition
BIOT is the standard laboratory abbreviation for biotinidase enzyme activity testing in newborn screening programs. This test measures the activity of the biotinidase enzyme, which is essential for recycling the vitamin biotin. Reduced or absent enzyme activity indicates biotinidase deficiency, a treatable metabolic disorder that can cause seizures, hearing loss, and developmental delays if undetected.
Usage
Usage note: Do not confuse with other laboratory abbreviations; always verify context when editing.
In Context
- "The BIOT result was below the cutoff value, requiring immediate follow-up testing." — Laboratory report
- "Program statistics showed a 2% repeat rate for BIOT assays due to insufficient specimen volume." — Quality metrics report
Don't confuse with
BIOM
BIO