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Technical
IVT
birth weight adjustment
Mathematical correction of screening results based on the infant's birth weight to improve test accuracy.
Full Definition
Birth weight adjustment is a statistical method used to normalize certain newborn screening analytes for the baby's birth weight, recognizing that metabolite concentrations vary with infant size and maturity. This adjustment is particularly important for premature infants and those with very low birth weights, as their physiological immaturity affects baseline analyte levels. The process helps reduce false positive rates while maintaining screening sensitivity.
Usage
Usage note: Specify which analytes undergo adjustment when describing protocols.
In Context
- "After birth weight adjustment, the 17-OHP value fell within the normal range for this 1200-gram infant." — Laboratory interpretation note
- "The program implemented birth weight adjustment algorithms to reduce referrals for premature infants." — Program improvement report
Also known as
weight normalization
weight correction
Don't confuse with
gestational age adjustment
age correction