late collection
Newborn screening specimens collected beyond the optimal timing window, potentially affecting test accuracy.
Full Definition
Late collection refers to newborn screening specimens obtained after the recommended collection timeframe, typically beyond 7 days of life. While specimens can still be tested, late collection may reduce sensitivity for certain conditions and delay treatment initiation if abnormal. Late collections often occur with early hospital discharge, NICU admissions, or home births. Programs may have specific protocols for handling late specimens, including modified cutoff values or additional testing requirements.
Usage
Usage note: Hyphenate when used as an adjective modifier.
In Context
- "Late collection specimens require careful interpretation due to age-related analyte changes." — Laboratory procedures manual
- "The program tracked late collection rates to identify areas for collection training improvement." — Quality improvement report