Intermediate
Technical
IVT
multiplex screening
Laboratory process that simultaneously tests for multiple disorders from a single blood sample.
Full Definition
A screening methodology that allows detection of numerous genetic and metabolic conditions using one dried blood spot specimen. This approach maximizes efficiency and reduces the need for multiple sample collections. Common in modern newborn screening programs where dozens of conditions can be assessed from a single heel stick sample. The technique relies on sophisticated analytical methods like tandem mass spectrometry to identify multiple analytes simultaneously.
Usage
Usage note: Distinguish from sequential testing where multiple separate assays are performed.
In Context
- "The laboratory implemented multiplex screening to detect 35 conditions from each newborn sample." — Laboratory protocol documentation
- "Multiplex screening has revolutionized newborn screening efficiency compared to historical single-disorder approaches." — Program evaluation report
Also known as
multi-analyte screening
panel testing
Contrasted with
single-condition screening
targeted screening
Don't confuse with
sequential screening
tiered screening