specimen adequacy
The quality assessment of collected blood samples to ensure reliable newborn screening test results.
Full Definition
Specimen adequacy evaluation involves systematic assessment of dried blood spot samples for factors that could compromise screening accuracy, including blood volume, saturation quality, layering, contamination, and proper collection technique. Inadequate specimens may result in false negatives or false positives, potentially missing treatable conditions or causing unnecessary anxiety. Quality indicators include complete filling of filter paper circles, absence of serum rings, appropriate saturation without clotting, and proper identification labeling.
Usage
Usage note: Use 'specimen adequacy' rather than 'sample adequacy' to maintain consistency with laboratory terminology.
In Context
- "Poor specimen adequacy resulted in a request for sample recollection before the infant's discharge." — Quality control report
- "Training programs emphasize proper collection techniques to ensure specimen adequacy." — Staff education material