thyroid stimulating hormone
A pituitary hormone measured in newborn screening to detect congenital hypothyroidism.
Full Definition
Thyroid stimulating hormone, also known as thyrotropin, is a glycoprotein hormone produced by the anterior pituitary that regulates thyroid gland function. In newborn screening for congenital hypothyroidism, elevated TSH levels indicate primary thyroid dysfunction requiring immediate evaluation and treatment. Early detection and thyroid hormone replacement therapy prevent intellectual disability, growth retardation, and other developmental complications associated with untreated congenital hypothyroidism.
Usage
Usage note: Spell out 'thyroid stimulating hormone' on first use, then use TSH. Note that it stimulates thyroid function rather than being produced by the thyroid.
In Context
- "Elevated thyroid stimulating hormone levels triggered an immediate pediatric endocrinology consultation." — Clinical follow-up protocol
- "The screening program measures thyroid stimulating hormone to identify congenital hypothyroidism cases." — Program description