Chloroprocaine
Short-acting ester local anesthetic used in obstetric anesthesia for its rapid onset and metabolism, particularly useful in emergency situations.
Full Definition
Chloroprocaine is an ester-type local anesthetic with rapid onset and short duration of action due to its quick hydrolysis by plasma pseudocholinesterases. In obstetric anesthesia, it is particularly valuable for emergency cesarean sections when rapid dense blockade is needed, epidural top-ups for inadequate labor analgesia, and situations where short-duration anesthesia is desired. The drug has minimal placental transfer and is rapidly metabolized, making it safe for both mother and fetus. However, it can cause significant motor blockade and has been associated with prolonged neurological deficits when used in high concentrations.
Usage
Usage note: Distinguish from other local anesthetics by its ester linkage and rapid metabolism; avoid high concentrations to prevent neurotoxicity.
In Context
- "Epidural chloroprocaine 3% was administered for emergency cesarean section due to its rapid onset." — Emergency anesthesia documentation
- "The short duration of chloroprocaine allowed for early ambulation after epidural top-up." — Postoperative recovery note