Oxytocin
Synthetic hormone used to induce or augment labor contractions and prevent postpartum hemorrhage, with significant anesthetic implications.
Full Definition
Oxytocin is a synthetic version of the naturally occurring hormone that stimulates uterine contractions and milk ejection. In obstetric practice, it is used to induce labor, augment weak contractions, and prevent or treat postpartum hemorrhage. From an anesthetic perspective, oxytocin administration can cause significant hypotension, particularly when given as a bolus dose, due to its vasodilatory effects. It also has antidiuretic properties and can cause water retention. Anesthesiologists must be aware of oxytocin's cardiovascular effects when managing patients during cesarean delivery or postpartum hemorrhage treatment.
Usage
Usage note: Distinguish from other uterotonic agents like ergometrine and carboprost, which have different mechanisms and side effect profiles.
In Context
- "Slow oxytocin infusion was initiated to prevent hypotension during cesarean delivery." — Intraoperative medication administration
- "The patient developed severe hypotension following rapid oxytocin bolus for uterine atony." — Adverse drug reaction report