HELLP syndrome
Pronunciation: HELL-p
Also written as: HELLP — Hemolysis, Elevated Liver enzymes, Low Platelet count
A severe variant of preeclampsia characterized by Hemolysis, Elevated Liver enzymes, and Low Platelet count.
Full Definition
HELLP syndrome is a life-threatening obstetric complication that represents a severe form of preeclampsia, characterized by a triad of hemolysis (breakdown of red blood cells), elevated liver enzymes indicating hepatocellular damage, and low platelet count (thrombocytopenia). It occurs in approximately 0.5-0.9% of all pregnancies and 10-20% of women with severe preeclampsia. HELLP syndrome can develop rapidly and may present without the classic signs of preeclampsia such as hypertension or proteinuria. Symptoms may include epigastric pain, nausea, vomiting, and malaise. Immediate delivery is usually indicated regardless of gestational age to prevent maternal mortality.
Usage
Usage note: Always capitalize as HELLP; remember it's a syndrome, not just elevated liver enzymes.
In Context
- "Laboratory results confirmed HELLP syndrome with severe thrombocytopenia and elevated transaminases." — Critical care assessment
- "Emergency delivery was indicated for HELLP syndrome at 32 weeks gestation despite fetal immaturity." — High-risk obstetric management plan