iris mammillations
Pronunciation: EYE-ris mam-ih-LAY-shuns
Small, nodular growths on the iris surface that may indicate iris melanoma or serve as a risk factor for malignant transformation.
Full Definition
Iris mammillations are small, dome-shaped nodular elevations that develop on the surface of iris lesions, particularly iris nevi and melanomas. These structures appear as tiny, rounded protrusions that can be observed during slit-lamp examination and represent areas of tumor growth extending toward the anterior chamber. The presence of mammillations is considered a clinical risk factor for malignant transformation of iris nevi and may indicate active growth in established iris melanomas. Their detection often prompts more frequent monitoring or consideration for biopsy, as they suggest biological activity within the lesion.
Usage
Usage note: Always use plural form 'mammillations' as these typically appear as multiple small nodules.
In Context
- "Multiple iris mammillations were noted during serial photography, suggesting tumor progression." — Ophthalmology examination note
- "The development of iris mammillations prompted surgical intervention for suspected melanoma." — Surgical consultation report