local tumor control
Also written as: LTC — Local Tumor Control
Successful prevention of tumor regrowth at the primary treatment site following oncologic intervention.
Full Definition
A primary endpoint in ocular oncology referring to the absence of tumor progression or recurrence at the original tumor location following treatment with radiation, surgery, or other modalities. Local control is typically assessed through serial imaging and clinical examinations over extended follow-up periods. High rates of local control are achievable with modern treatment techniques, but the definition may vary between studies regarding what constitutes treatment failure versus stable disease with minimal residual tumor.
Usage
Usage note: Specify the follow-up duration and criteria used to define control in research contexts.
In Context
- "The study reported 95% local tumor control at five years following episcleral plaque therapy." — clinical research publication
- "Excellent local tumor control was maintained despite minimal residual tumor thickness on ultrasonography." — long-term follow-up assessment