TNMH staging
Pronunciation: T-N-M-H staging
Also written as: TNMH — Tumor, Nodal involvement, Metastases, Histopathology
Staging system for uveal melanoma using Tumor size, Nodal involvement, Metastases, and Histopathology.
Full Definition
TNMH staging is a comprehensive staging system specifically developed for uveal melanoma that incorporates four key components: Tumor size (largest basal diameter and thickness), Nodal involvement, distant Metastases, and Histopathology (cell type and other microscopic features). This system provides more precise prognostic information than traditional TNM staging alone. The histopathologic component includes factors such as cell type, mitotic rate, and presence of epithelioid cells, which are crucial prognostic indicators in uveal melanoma.
Usage
Usage note: Specific to uveal melanoma; do not confuse with standard TNM staging.
In Context
- "The uveal melanoma was classified as T3N0M0H2 using the TNMH staging system." — Pathology report
- "TNMH staging provides superior prognostic accuracy compared to TNM staging alone in uveal melanoma." — Clinical research paper