vitreous seeding
The spread of tumor cells into the vitreous cavity, commonly seen in advanced retinoblastoma.
Full Definition
Vitreous seeding refers to the dissemination of malignant cells from an intraocular tumor into the vitreous cavity, creating secondary tumor deposits that appear as white, fluffy masses or dust-like particles suspended in the vitreous gel. This phenomenon is most commonly associated with retinoblastoma but can also occur with other intraocular malignancies. Vitreous seeding significantly impacts staging, prognosis, and treatment planning, often necessitating more aggressive therapeutic approaches including intravitreal chemotherapy or enucleation. The presence and extent of vitreous seeding is carefully documented using standardized classification systems and influences risk stratification for treatment protocols.
Usage
Usage note: Document location, extent, and morphological characteristics of seeding when present.
In Context
- "Extensive vitreous seeding was noted throughout the inferior vitreous cavity on B-scan ultrasonography." — Imaging report
- "The patient received three cycles of intravitreal melphalan for vitreous seeding control." — Treatment protocol documentation