hepatobiliary phase
Delayed imaging phase showing liver-specific contrast agent uptake by functioning hepatocytes.
Full Definition
The hepatobiliary phase is a delayed imaging phase obtained 15-20 minutes after injection of liver-specific MRI contrast agents such as gadoxetic acid. During this phase, functioning hepatocytes take up and concentrate the contrast agent, providing information about hepatocellular function. Normal liver parenchyma appears hyperintense, while lesions lacking functioning hepatocytes appear hypointense. This phase is particularly valuable for detecting small hepatocellular carcinomas, characterizing focal nodular hyperplasia, and assessing liver function. The hepatobiliary phase adds functional information to morphologic imaging, improving diagnostic confidence in hepatic lesion characterization.
Usage
Usage note: Specify contrast agent type when reporting hepatobiliary phase findings.
In Context
- "Hepatobiliary phase images showed multiple hypointense nodules consistent with hepatocellular carcinoma." — Liver MRI report
- "The lesion demonstrated central enhancement on hepatobiliary phase, supporting focal nodular hyperplasia diagnosis." — Hepatic lesion characterization