Perfusion-Weighted Imaging
Pronunciation: P-W-I
Also written as: PWI — Perfusion-Weighted Imaging
MRI technique measuring tissue blood flow and vascular characteristics using contrast bolus tracking.
Full Definition
Perfusion-Weighted Imaging is an MRI technique that assesses tissue blood flow and microvascular characteristics by tracking the passage of contrast material through tissue capillary beds. PWI generates parametric maps including cerebral blood flow, cerebral blood volume, and mean transit time, which are particularly valuable in neuro-oncology for differentiating tumor recurrence from treatment-related changes. The technique helps characterize tumor vascularity, assess treatment response to anti-angiogenic therapies, and guide treatment planning by identifying areas of viable tumor tissue.
Usage
Usage note: Specify whether using dynamic susceptibility contrast or dynamic contrast enhancement technique.
In Context
- "PWI demonstrated increased cerebral blood volume in the enhancing portion of the lesion." — Neuro-oncology MRI report
- "Perfusion-weighted imaging helped distinguish tumor recurrence from radiation necrosis." — Follow-up brain MRI