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Intermediate Technical IVT

RECIST measurable disease

Tumor lesions meeting size criteria for objective response assessment under RECIST guidelines.

Full Definition

RECIST measurable disease refers to tumor lesions that meet specific size and imaging criteria allowing for objective assessment of treatment response according to Response Evaluation Criteria in Solid Tumors. Measurable lesions must have a longest diameter ≥10mm on CT (≥15mm for lymph nodes) and be suitable for accurate repeated measurements. These lesions are designated as target lesions and form the basis for calculating overall response including complete response, partial response, stable disease, and progressive disease. Non-measurable disease includes lesions that are too small, poorly defined, or technically difficult to measure accurately, and these are classified as non-target lesions with qualitative assessment only.

Usage

Usage note: Specify RECIST version (1.1 is current) as size criteria have changed between versions.

In Context

  • "Three hepatic lesions qualified as RECIST measurable disease and were designated as target lesions." — baseline tumor assessment
  • "The lung nodules were too small to constitute RECIST measurable disease." — response evaluation report

Also known as

target lesions measurable lesions

Contrasted with

non-measurable disease non-target lesions

Don't confuse with

evaluable disease bidimensional measurements

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