Treatment Response Assessment in Neuro-Oncology
Pronunciation: RAH-no
Also written as: RANO — Response Assessment in Neuro-Oncology
Standardized criteria for evaluating treatment response in brain tumors through imaging and clinical assessment.
Full Definition
RANO criteria provide a standardized framework for assessing treatment response in neuro-oncology patients, incorporating both imaging parameters and clinical status. Unlike RECIST criteria used for systemic cancers, RANO accounts for the unique challenges of brain tumor assessment including blood-brain barrier effects, steroid use, and pseudoprogression. The criteria help distinguish true tumor progression from treatment-related changes, which is critical for clinical decision-making and research studies in neuro-oncology.
Usage
Usage note: Always capitalize as RANO when used as acronym; spell out on first use in formal documents.
In Context
- "The radiologist applied RANO criteria to evaluate the patient's response to temozolomide therapy." — Radiology report
- "According to RANO guidelines, this patient demonstrates stable disease with no new enhancing lesions." — Clinical assessment