HIPEC
Pronunciation: /ˈhaɪpɛk/
Also written as: HIPEC — Hyperthermic Intraperitoneal Chemotherapy
Heated intraperitoneal chemotherapy administered directly into the abdominal cavity during surgery.
Full Definition
Hyperthermic intraperitoneal chemotherapy (HIPEC) is a specialized treatment technique where heated chemotherapy drugs are circulated directly within the peritoneal cavity during surgery. The procedure typically follows cytoreductive surgery and involves filling the abdomen with heated chemotherapy solution to target microscopic cancer cells that may remain after tumor removal. The heat enhances drug penetration and effectiveness while the direct application maximizes local concentration while minimizing systemic toxicity.
Usage
Usage note: Always capitalized as HIPEC; do not confuse with PIPAC (Pressurized Intraperitoneal Aerosol Chemotherapy).
In Context
- "The patient tolerated HIPEC well with no immediate post-operative complications." — Post-operative note
- "HIPEC was performed using mitomycin C at 42°C for 90 minutes." — Procedure report