tumor capsule
The fibrous tissue layer that may surround certain tumors, creating a natural boundary between malignant tissue and normal structures.
Full Definition
A fibrous connective tissue layer that forms around some tumors, particularly certain sarcomas and well-differentiated cancers. The presence and integrity of a tumor capsule influences surgical planning and oncologic outcomes. Editors should note that 'pseudocapsule' refers to compressed normal tissue rather than true capsular formation, and the distinction affects surgical approach and prognosis reporting.
Usage
Usage note: Distinguish from 'pseudocapsule' which represents compressed normal tissue rather than true capsular formation.
In Context
- "The well-encapsulated renal cell carcinoma was removed with an intact tumor capsule." — Surgical pathology report
- "Violation of the tumor capsule during dissection may increase local recurrence risk." — Operative note