genomic sequencing panel
Targeted genetic testing that analyzes multiple cancer-related genes simultaneously to guide precision oncology treatment decisions.
Full Definition
A genomic sequencing panel is a comprehensive molecular diagnostic test that examines multiple genes simultaneously to identify mutations, copy number variations, and other genomic alterations relevant to cancer diagnosis and treatment. These panels typically focus on clinically actionable genes that may influence treatment selection, including those associated with targeted therapies, immunotherapies, or clinical trial eligibility. Panel testing is more efficient and cost-effective than sequential single-gene testing, providing oncologists with crucial information for precision medicine approaches. The results require careful interpretation by molecular pathologists and genetic counselors, and the data must be integrated with clinical information systems to support treatment decision-making.
Usage
Usage note: Use specific panel names when available (e.g., 'Foundation Medicine panel'); avoid confusing with broader genomic testing approaches.
In Context
- "The 50-gene sequencing panel identified actionable mutations in BRCA1 and PIK3CA." — Molecular pathology report
- "Genomic sequencing panel results must be integrated with the patient's EHR for clinical decision support." — Laboratory information system