molecular tumor board
Also written as: MTB — Molecular Tumor Board
Specialized multidisciplinary meeting focused on interpreting genomic testing results and selecting precision oncology treatments based on molecular findings.
Full Definition
A molecular tumor board (MTB) is a specialized multidisciplinary conference that brings together oncologists, molecular pathologists, geneticists, bioinformaticians, and pharmacists to review and interpret genomic testing results for cancer patients. Unlike traditional tumor boards that focus on staging and standard treatment approaches, MTBs specifically address precision medicine questions, including the clinical significance of detected mutations, potential targeted therapies, clinical trial opportunities, and treatment sequencing strategies based on molecular findings. These meetings require expertise in genomic interpretation, drug mechanisms of action, and the evolving landscape of precision oncology. MTB recommendations often involve complex decision-making about off-label drug use, clinical trial enrollment, and the integration of molecular findings with standard clinical parameters.
Usage
Usage note: Distinguish clearly from traditional tumor boards; emphasize the molecular/genomic focus of these specialized meetings.
In Context
- "The molecular tumor board recommended targeted therapy based on the patient's EGFR mutation status." — Precision medicine consultation
- "Molecular tumor board discussions require integration of genomic data with clinical and pathological findings." — Medical meeting documentation