choroidal neovascularization
Pronunciation: koh-roy-dal nee-oh-vas-kyuh-lah-rih-ZAY-shun
Also written as: CNV — choroidal neovascularization
Abnormal blood vessel growth from the choroid through Bruch's membrane into the subretinal space.
Full Definition
Choroidal neovascularization (CNV) is the pathological growth of new blood vessels from the choroidal circulation that breach Bruch's membrane and extend into the subretinal or sub-retinal pigment epithelium space. This process is commonly associated with age-related macular degeneration, but can also occur in conditions like pathologic myopia, inflammatory diseases, and hereditary disorders. CNV can lead to fluid leakage, hemorrhage, and fibrous scarring, resulting in severe central vision loss if left untreated.
Usage
Usage note: Specify the underlying cause and whether the CNV is active or inactive.
In Context
- "Fluorescein angiography confirmed active choroidal neovascularization in the right macula." — Diagnostic imaging report
- "Anti-VEGF therapy was initiated to treat choroidal neovascularization secondary to AMD." — Treatment plan