intravitreal injection
Pronunciation: in-tra-VIT-ree-al in-JEK-shun
Direct injection of medication into the vitreous cavity of the eye through the pars plana.
Full Definition
An intravitreal injection is a minimally invasive procedure that delivers medication directly into the vitreous humor, the gel-like substance filling the posterior chamber of the eye. The injection is performed through the pars plana using a fine gauge needle, typically 27-30 gauge, under sterile conditions. This route of drug delivery allows for high local drug concentrations while minimizing systemic exposure, making it ideal for treating retinal diseases such as diabetic macular edema, age-related macular degeneration, and retinal vein occlusions. The procedure has become a cornerstone of modern retinal therapy, with millions performed annually worldwide.
Usage
Usage note: Commonly abbreviated as 'IVT' in medical records; always specify the injected medication.
In Context
- "Monthly intravitreal injections of anti-VEGF agents stabilized the patient's macular edema." — Treatment protocol
- "The risk of endophthalmitis following intravitreal injection is less than 0.1% with proper technique." — Safety guideline