Glandular Odontogenic Cyst
A rare, locally aggressive odontogenic cyst of the jaws characterised by a unique epithelial lining with glandular and mucous cell features, associated with a high recurrence rate.
Full Definition
The glandular odontogenic cyst (GOC), also known as sialo-odontogenic cyst, is a rare jaw cyst with a distinctive lining that includes cuboidal or columnar surface cells, mucous cells, intraepithelial crypts, and cilia. It most commonly occurs in the anterior mandible in middle-aged to older adults. Despite its benign nature, the GOC is considered locally aggressive and has a recurrence rate of up to 30% following conservative enucleation, necessitating more aggressive surgical management. Editors must distinguish GOC from the calcifying odontogenic cyst and botryoid odontogenic cyst, with which it shares overlapping features. The sialo-odontogenic cyst designation, while used in some older literature, is now largely superseded.
Usage
Usage note: The synonym 'sialo-odontogenic cyst' is outdated; flag for replacement with 'glandular odontogenic cyst' in submitted manuscripts.
In Context
- "The resection specimen was diagnosed as a glandular odontogenic cyst with mucous cell differentiation and intraepithelial crypts." — Surgical pathology report
- "The editor noted that the author had used 'sialo-odontogenic cyst' throughout and queried whether the current preferred term 'glandular odontogenic cyst' should be substituted." — Manuscript query