Ossifying Fibroma
A benign fibro-osseous lesion of the jaws characterised by replacement of normal bone by fibrous tissue containing varying amounts of mineralised material including woven bone trabeculae and cementum-like spherules.
Full Definition
Ossifying Fibroma is a well-demarcated benign fibro-osseous lesion that arises most commonly in the tooth-bearing regions of the mandible. Histologically it consists of a cellular fibrous stroma in which woven and lamellar bone trabeculae and/or cementum-like calcifications are deposited. Unlike fibrous dysplasia, ossifying fibroma is typically encapsulated and can be shelled out surgically. Editors frequently encounter the need to distinguish this term from 'cemento-ossifying fibroma' and 'peripheral ossifying fibroma,' which are separate entities with different behaviour; precise use of the full preferred name is therefore critical. WHO nosology groups these under the fibro-osseous lesion category.
Usage
Usage note: Editors must preserve the precise modifier: 'ossifying fibroma,' 'cemento-ossifying fibroma,' and 'peripheral ossifying fibroma' are distinct entities and should not be conflated or shortened to 'OF' without prior expansion.
In Context
- "The biopsy report confirmed ossifying fibroma with a well-defined fibrous capsule and scattered cementum-like deposits." — Oral Pathology Report
- "The editor changed 'fibrous lesion' to 'ossifying fibroma' to match the histopathological diagnosis stated in the abstract." — Case Report Manuscript