Squamous Odontogenic Tumour
Also written as: SOT — Squamous Odontogenic Tumour
A rare, locally infiltrative benign odontogenic neoplasm composed of islands of well-differentiated squamous epithelium within a fibrous stroma, lacking the stellate reticulum seen in ameloblastoma.
Full Definition
Squamous Odontogenic Tumour (SOT) is a benign but locally infiltrative neoplasm of odontogenic origin, arising from rests of Malassez or other remnants of the dental lamina. Its defining histological feature is islands of mature, well-differentiated squamous epithelium that are flat-based and lack the peripheral palisading or stellate reticulum characteristic of ameloblastoma. It commonly presents as a triangular radiolucency on periapical radiographs adjacent to tooth roots. Editors should be aware that SOT may be confused with well-differentiated squamous cell carcinoma, and pathology reports must include clear language distinguishing the two. The acronym SOT is far less commonly encountered than OSCC or CEOT and should always be expanded on first use.
Usage
Usage note: Expand 'SOT' on first use in all document types. Do not conflate with 'OSCC' or general squamous cell carcinoma; reports should explicitly state the benign nature of this tumour.
In Context
- "The pathologist's report described nests of bland squamous epithelium consistent with Squamous Odontogenic Tumour (SOT) rather than a carcinomatous process." — Surgical Pathology Report
- "During copy-editing, the author's use of 'SOT' was flagged as requiring expansion on first mention." — Journal Manuscript