Frictional Keratosis
A benign, white keratotic lesion of the oral mucosa arising as a protective response to repeated mechanical trauma, which resolves upon elimination of the causative friction.
Full Definition
Frictional keratosis is the most common white lesion of the oral mucosa and is considered a reactive, not dysplastic, change. Typical sites include the linea alba of the buccal mucosa (at the occlusal line), the edentulous alveolar ridge, and areas adjacent to broken teeth or ill-fitting appliances. The hallmark feature distinguishing it from potentially malignant leukoplakia is its resolution within two to four weeks once the source of friction is removed. Histologically it shows hyperparakeratosis or hyperorthokeratosis without epithelial dysplasia. Editors must ensure that frictional keratosis is not labelled as leukoplakia unless the lesion persists after removal of the causative factor.
Usage
Usage note: Key editorial distinction: frictional keratosis resolves when the irritant is removed; leukoplakia does not. Do not label a resolving white lesion as leukoplakia in clinical documents.
In Context
- "The white patch along the occlusal line was diagnosed as frictional keratosis attributable to habitual cheek chewing and resolved after the habit was discontinued." — Clinical case notes
- "The editor queried whether the lesion should be reclassified as leukoplakia; the author responded that it had resolved completely on removal of the irritant, confirming frictional keratosis." — Peer review correspondence