Potentially Malignant Disorder
Also written as: PMD
A WHO-endorsed term for oral mucosal conditions that carry an increased risk of transforming into oral squamous cell carcinoma.
Full Definition
The term 'potentially malignant disorder' (PMD) replaced the older term 'precancerous lesion or condition' following a WHO workshop in 2005, and editors should use the current terminology unless the document specifically discusses historical classification. PMDs of the oral cavity include leukoplakia, erythroplakia, oral submucous fibrosis, oral lichen planus, and actinic cheilitis, among others. The term emphasises that not all such lesions will transform and that the risk varies by lesion type and patient factors. Editors should flag the outdated term 'precancerous' and query whether the author wishes to update to current WHO terminology.
Usage
Usage note: Flag 'precancerous' or 'premalignant' as outdated when encountered in contemporary oral medicine manuscripts. Use PMD or OPMD per the author's chosen convention.
In Context
- "The consensus statement recommended annual review for all patients diagnosed with an oral potentially malignant disorder (PMD)." — Clinical guideline
- "Authors using the term 'precancerous lesion' should be queried about updating to 'potentially malignant disorder' in line with current WHO guidance." — Manuscript editor's note