Skip to main content
Professional Technical IVT

Bupivacaine

Pronunciation: byoo-PIV-ah-kane

Long-acting local anesthetic commonly used in oral surgery for extended postoperative pain control.

Full Definition

Bupivacaine is an amide-type local anesthetic with a duration of action ranging from 4-8 hours, making it particularly valuable in oral surgical procedures requiring prolonged numbness. It is available in various concentrations (0.25%, 0.5%, 0.75%) and may be combined with epinephrine for enhanced hemostasis and duration. The drug blocks sodium channels in nerve membranes, preventing pain signal transmission. Due to its cardiotoxic potential at high doses, careful attention to maximum dosing guidelines is essential.

Usage

Usage note: Always specify concentration and presence/absence of vasoconstrictor in documentation.

In Context

  • "The extraction sites were infiltrated with 0.5% bupivacaine with epinephrine for extended postoperative analgesia." — Operative report
  • "Maximum safe dosage of bupivacaine is 2.5 mg/kg body weight for healthy adults." — Anesthesia protocol

Also known as

Marcaine Sensorcaine

Don't confuse with

lidocaine articaine

Editors from these organisations have used our services since 1998

Reuters BBC Oxford University Press Penguin Random House Springer Microsoft Suncor Energy United Nations Fisher Investments IBM The Home Depot KODAK CHEVRON