Advanced
Technical
IVT
platelet-rich fibrin
A concentrated preparation of platelets and growth factors derived from the patient's blood to enhance healing.
Full Definition
Platelet-rich fibrin (PRF) is a second-generation platelet concentrate that forms a natural fibrin matrix containing platelets, leukocytes, and growth factors. Unlike platelet-rich plasma (PRP), PRF requires no anticoagulants or additives and forms a stable clot that releases growth factors slowly over time. It is used to enhance soft tissue healing, bone regeneration, and reduce post-operative complications. PRF is commonly applied in extraction sockets, sinus augmentation procedures, and periodontal regenerative therapy.
Usage
Usage note: Distinguish from PRP (platelet-rich plasma) which has different preparation and properties.
In Context
- "Platelet-rich fibrin was placed in the extraction socket to promote healing and reduce dry socket risk." — Post-extraction procedure
- "The PRF membrane was used to cover the bone graft and enhance regeneration." — Regenerative surgery documentation
Also known as
PRF
Don't confuse with
platelet-rich plasma
PRP