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sequestrum
Pronunciation: sih-KWES-trum
A piece of necrotic bone that has separated from healthy bone tissue.
Full Definition
A sequestrum is a fragment of dead bone that has become separated from the surrounding healthy bone due to infection, trauma, or compromised blood supply. The body attempts to isolate the necrotic tissue by forming new bone around it (involucrum). Sequestra commonly occur following osteomyelitis, bisphosphonate-related osteonecrosis, or radiation therapy. Treatment typically involves surgical removal (sequestrectomy) to eliminate the source of infection and promote healing.
Usage
Usage note: Plural form is 'sequestra'. Do not confuse with 'involucrum' which is the new bone formed around the sequestrum.
In Context
- "Radiographic examination revealed a radiopaque sequestrum in the mandibular body." — Diagnostic imaging report
- "Surgical removal of the sequestrum was necessary to resolve the chronic infection." — Treatment planning documentation
Also known as
necrotic bone fragment
Contrasted with
vital bone
healthy bone
Don't confuse with
involucrum
osteophyte