oncological margin
The amount of normal tissue removed around a tumor to ensure complete excision and minimize local recurrence risk.
Full Definition
An oncological margin refers to the zone of normal tissue that must be removed around a malignant tumor to achieve adequate local control and minimize the risk of local recurrence. In orthopedic oncology, achieving appropriate oncological margins is fundamental to successful limb-salvage surgery. The required margin width varies by tumor type, grade, and location, but generally ranges from 1-3 centimeters of normal tissue in all directions. Achieving adequate margins while preserving limb function requires careful preoperative planning using advanced imaging and may involve complex reconstruction techniques. Positive margins significantly increase local recurrence risk and may necessitate re-excision or adjuvant treatment.
Usage
Usage note: Use 'oncological' rather than 'oncologic' for consistency with international usage.
In Context
- "Achieving adequate oncological margins required en bloc resection of the entire compartment." — Surgical planning discussion
- "Final pathology confirmed negative oncological margins throughout the resection specimen." — Pathology report