Perthes Disease
Pronunciation: PER-tez dih-ZEEZ
A pediatric condition involving avascular necrosis of the femoral head, also known as Legg-Calvé-Perthes disease.
Full Definition
Perthes disease, formally known as Legg-Calvé-Perthes disease, is a childhood condition characterized by temporary loss of blood supply to the femoral head, leading to bone death and subsequent regeneration. Named after three physicians who independently described it, the disease typically affects children aged 4-10 years and is more common in boys. The condition progresses through four stages: initial necrosis, fragmentation, reossification, and remodeling. Treatment ranges from observation to surgical intervention depending on age, extent of involvement, and hip containment.
Usage
Usage note: May be written as Perthes disease or full eponym Legg-Calvé-Perthes disease. Note the diacritic in Calvé.
In Context
- "The 7-year-old patient was diagnosed with Perthes disease affecting the right hip." — Pediatric orthopedic consultation
- "Radiographs showed classic fragmentation stage of Legg-Calvé-Perthes disease." — Imaging report