cerebral perfusion pressure
The pressure gradient driving cerebral blood flow, calculated as mean arterial pressure minus intracranial pressure, critical for managing pediatric traumatic brain injury.
Full Definition
Cerebral perfusion pressure (CPP) represents the pressure gradient that drives blood flow through the cerebral circulation and is calculated by subtracting intracranial pressure (ICP) from mean arterial pressure (MAP). In pediatric critical care, maintaining adequate CPP is essential for preventing secondary brain injury in patients with traumatic brain injury, stroke, or other conditions causing elevated ICP. Age-appropriate CPP targets are crucial as pediatric patients have different physiologic requirements than adults. Typical pediatric CPP targets range from 40-50 mmHg in infants to 50-60 mmHg in older children, though individualized targets may be necessary based on the clinical scenario and cerebral autoregulation status.
Usage
Usage note: Often abbreviated as CPP in clinical documentation.
In Context
- "The patient's cerebral perfusion pressure was maintained above 50 mmHg through vasopressor support and ICP management." — Neurocritical care plan
- "Continuous monitoring revealed episodes of compromised cerebral perfusion pressure requiring immediate intervention." — Neurologic assessment report