transposition of great arteries
A congenital heart defect where the aorta and pulmonary artery are switched, creating two parallel circuits.
Full Definition
Transposition of the great arteries (TGA) is a cyanotic congenital heart disease where the aorta and pulmonary artery arise from the incorrect ventricles, creating two separate parallel circuits. In simple TGA, the right ventricle gives rise to the aorta while the left ventricle connects to the pulmonary artery, resulting in deoxygenated blood circulating to the body. This condition is incompatible with life unless mixing occurs through atrial septal defect, ventricular septal defect, or patent ductus arteriosus. Treatment typically involves balloon atrial septostomy in the neonatal period followed by arterial switch operation within the first weeks to months of life.
Usage
Usage note: Distinguish between d-TGA (simple) and l-TGA (congenitally corrected). TGA acceptable after first use.
In Context
- "The newborn with transposition of great arteries underwent emergent balloon atrial septostomy to improve mixing." — Cardiac catheterization report
- "TGA repair via arterial switch operation was planned within the first month of life." — Cardiothoracic surgery consultation